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The Center for Chemical Genomics provides high-throughput screening of extensive small molecule, natural product and siRNA libraries along with assay development and optimization for basic biology and drug discovery projects. For collaboration, please contact Dr. Michael Weiss at weissma@iu.edu , (317)274-8025. Multi-Omics Core Facility Services The IIGB core facilities are housed in Noel Keen Hall and aim to provide multi-omics services to researchers at UCR and colleagues at other institutions. small molecule informatics, design and synthesis. Chemical Genomics Core Facility The Chemical Genomics Core Facility (CGCF) at the Indiana University School of Medicine seeks to provide sophisticated small molecule informatics, design and synthesis ; to facilitate faculty-driven high-throughput screening and high-content analysis; and to perform small and large molecule analysis for academic and industrial investigators. The BPF NGS Genomics Core Facility provides state of the art resources and services including NextGen Sequencing on the Illumina platform, NGS Sample Preparation (for a variety of DNA and RNA applications), Single Cell Analysis on the 10X Genomics Chromium platform, DNA and RNA Quality Assessment, Sanger DNA Sequencing, DNA/RNA isolation and purification, CGgj~}w0?ZTC;T%##=\f-y|bgn7G+2cS&ZVW.ey2vZUK}}c+'I&Lyr'hgf? It is also connected to the Chemical Proteomics and Proteogenomics node at SciLifeLab. Bioinformatics. Training in nucleic acid laboratory techniques is also available through the Genomics Core. The Chemical Genomics Core Director is responsible for resolving any concerns/issues including but not limited to services or data obtained within the CGCF, billing, authorship, and conflict of interest. The Chemical Genomics Core Facility (CGCF) at the Indiana University School of Medicine seeks to provide sophisticated small molecule informatics, design and synthesis; to facilitate faculty-driven high-throughput screening and high-content analysis; and to perform small and large molecule analysis for academic and industrial investigators. Contact Michael Weiss, PhD, MD, to inquire about collaborating with the Chemical Genomics Core Facility. Purdue University. endstream endobj 18 0 obj <>stream Facility Link . The Chemical Genomics Core Facility (CGCF) is a shared facility of the IU Simon Cancer Center and IU School of Medicine. 6. Types of projects we do: Whole Genome Sequencing (WGS) or Whole Genome Bisulphite Sequencing (WGBS) analysis of The four facilities within the chemical and environmental characterization core offer instruments and expert services to characterize the behavior and properties of a wide range of organic, inorganic and biological materials, including: proteins, DNA, lipids and other biomolecules; tissue, organic matter and small animals (such as insects) More about the CPP facility. The Genomics and Bioinformatics Shared Resource (GBSR) offers a central service that uses cutting-edge and high-throughput genomic technologies combined with expert data analysis. More information about the role of core facilities can be found on the about core facilities page. Overview. Chemical Genomics Core Facility of Indiana University School of Medicine We are enthusiastic in participating and/or supporting your screening projects through acquisition of outside funding. Chemical Genomics Core Facility of Indiana University School of Medicine : Price Schedule - HTS Price Schedule - Chemistry and Informatics Price Schedule - Synthetic and Analytical Equipment . Should a satisfactory resolution not be reached between the Core Director and the investigator(s), the CGCF Advisory Committee may be consulted. *Functional Genomics Core Facility (MGM) *Microbiome Core Facility (GCB/MGM) *Molecular Genomics Core (DMPI) Biochemical Analysis, and Chemical Synthesis. Genome-wide DNA methylation analysis: Methyl/BS-Seq. De novosequencing & re-sequencing of genomic DNA. Download PDF (12 KB) Abstract. We have a Services. This Facilities Core is overseen by Drs. Molecular Interactions Core Facility BIACORE is an optical biosensor that uses surface plasmon resonance (SPR) for real-time monitoring of macromolecular interactions without the need for labels. The overall goal of the proposed Computational Chemical Genomics Screening Center (CCGSC) is to build a research/teaching platform and collaboration services by providing new exploratory computational tools/algorithms and chemical libraries resources in a chemical genomics scale for in-silico drug design and discovery. The core is fully equipped for automated high throughput screening and modern chemical synthesis. Mission and Goal of CCGS Center. Chemical Genomics Core Facility of Indiana University School of Medicine : Price Schedule - HTS Price Schedule - Chemistry and Informatics Price Schedule - Synthetic and Analytical Equipment . Clean Room Facility. The Functional Genomics Core (FGC) provides capacity for high-throughput chemical, RNAi, and deletion library-based screens for the purpose of network analysis, drug and target discovery. Our Services: Assay development, implementation, validation and miniaturization specific to The ability to sequence DNA and to detect the expression thousands of genes in parallel has become a mainstay of 21st century biology. 26 Genomic Core Facility Manager jobs available on Indeed.com. vD j pnEi:Iw. By Lan Chen, Li Wu, Andrea Gunawan and Zhong-Yin Zhang. Genome-wide location analysis of nucleic acid-protein interactions ChIP-Seq, CLIP-Seq. The mission of CGCF is to provide excellence and innovation in high throughput screening (HTS) and medicinal chemistry. The Chemical Genomics Core Facility (CGCF) is a shared facility of the IU Simon Cancer Center and IU School of Medicine. Each Core Facility is spearheaded by a PhD-level Academic Coordinator, who metagenomics, and chemical genomics. The UTMB Gulf Coast Consortia Chemical Genomics Screening Core Facility (Director, Dr. Jia Zhou) Research Core Facilities. Directed by Dr. Terri Bruce, the imaging facility houses a number of advanced light microscopes, including a Leica SP8X Multiphoton spectral confocal microscope, and a Targeted enrichment (sequence capture) in solution coupled with MPS Genomics Core Facility (Huck) Providing next-generation sequencing and a number of traditional genomic services to the Penn State community as well as those outside the University. The UTMB Gulf Coast Consortia Chemical Genomics Screening Core Facility (Director, Dr. Jia Zhou)Research Core Facilities. hX[s6~#c1_i]qNN Ep (Nfb;9mj60gA[g JCV/3ony}no>~#[~^~g%qZ""bq!40EElZ [Ds%m^7\f n`o;lO26cf5 GeneCore provides the following analyses in a single- or a pair-end sequencing mode, including multiplexing and mate-pair libraries: 1. Aus den Ergebnissen dieser grundlegenden Arbeiten sollen neue Anstze zur Vorbeugung, Diagnostik und Therapie entwickelt werden. The aim of the Genomics Facility is to serve the research community both on and off campus with the resources and support researcher to achieve their goals. Affinity measurements, binding kinetics, active concentrations, binding specificity and epitope mapping. Within the Genomics Core, DNA sequencing supports research across the campus and extends to projects in collaboration with other institutions, including the sequencing of genomes, RNASeq, ChIPSeq, methylSeq, metagenomics and other applications. Associate Director of Chemical Genomics Facility, Purdue Institute for Drug Discovery, Purdue University West Lafayette, Indiana 207 connections. This facility allows direct analysis of the chemical and electronic properties of various forms of condensed matter that are at the forefront of scientific and technological innovation. The Bioimaging and Chemical Analysis Facilities Core is a central resource in analytical chemistry, separation science, metabolomics, and proteomics for Center members, and provides research participants with analytical expertise, training, and access to state-of-the-art instrumentation. 2. Contact Lifan Zeng, PhD, to request medicinal and analytical chemistry services. In order to facilitate multi-omics research, we have established Genomics, Proteomics, Metabolomics, Microscopy and Bioinformatics core facilities on campus. Induced Pluripotent Stem Cells (iPSC) Core Facility The Induced Pluripotent Stem Cells (iPSC) Core aims to expedite the use of iPSC technology. The Epigenomics and DNA Sequencing Core Facility managed by Greg Solomon, Ph.D. provides NextGen Sequencing (NGS) and Sanger Sequencing services to researchers throughout the NIEHS community.. Background. Bioinformatics providing resources for large-scale comparative genomics, data mining, systems modeling, and drug discovery. poster abstractThe Chemical Genomics Core Facility (CGCF) is a shared facility of the IU Simon Cancer Center and IU School of Medicine. To submit samples for. The core is fully equipped for automated high throughput screening and modern chemical synthesis. The Molecular Genomics Core Facility provides intramural researchers with access to cutting edge genotyping, microarray, Nanostring, nucleic acid isolation, and sequencing services. The mission of CGCF is to provide excellence and innovation in high throughput screening (HTS) and medicinal chemistry. Join to Connect. The core strives to support this work with technical and bioinformatics components for every project. (2018). CHEMICAL GENOMICS CORE FACILITY . RII-Funded. The core is equipped with five hoods for chemical synthesis, a microwave reactor, a parallel synthesizer and a preparative HPLC; a collection of 227,680 diversified small molecules, liquid handling and assay detection systems; and analytical instruments such as LC/Q-ToF and NMR. The core is fully equipped for automated high throughput screening and modern chemical synthesis. The facility is located at Biomedicum, Campus Solna, and specializes in supporting target identification and validation, keys and bottlenecks of drug discovery and development. Transcriptome sequencing: RNA-Seq. {^Sh6a$qdaA{,hU^C.7 VKa.c]ZZ-ar*dn0 N r Protein Production, Biochemical Analysis, and Chemical Synthesis. The CGCF is located in the Van Nuys Medical Science Building in Indianapolis. 4. f,o?-KlCctVF"ei'&GGx Bogdan Fedeles and Michael DeMott. Bogdan Fedeles and Michael DeMott. Our Services: Assay development, implementation, validation and miniaturization specific to the target of your interest. This Facilities Core is overseen by Drs. The Chemical Genomics Core Facility (CGCF) at the Indiana University School of Medicine seeks to provide sophisticated small molecule informatics, design and synthesis; to facilitate faculty-driven high-throughput screeningand high-content analysis; and to perform small and large molecule analysis for academic and industrial investigators. Chemical Proteomics Core Facility. Expert cytometry technicians are available to assist with any analysis or sorting experiments, with services available to all The mission of CGCF is to provide excellence and innovation in high throughput screening (HTS) and medicinal chemistry. The ability to sequence DNA and to detect the expression thousands of genes in parallel has become a mainstay of 21st century biology. The Chemical Genomics Core Facility (CGCF) is a shared facility of the IU Simon Cancer Center and IU School of Medicine. We have a We have several core facilities to meet this need. *4" au3cc1}|a-7oktu2w| Das Krebsforschungszentrum hat die Aufgabe, die Mechanismen der Krebsentstehung systematisch zu erforschen und Risikofaktoren fr Krebserkrankungen zu erfassen. A core facility is a specialist laboratory serving researchers from both within and outside its own institution. The Chemical Engineering cleanroom, a class 1000 cleanroom, is located on the 3rd floor of the HH Dow building. The Flow Cytometry Core Facility offers state-of-the-art, fully equipped flow cytometry instrumentation in two locations on the Dana-Farber campus. The mission of CGCF is to provide excellence and innovation in high throughput screening (HTS) and medicinal chemistry. Apply to Research Scientist, Professor, Development Operations Manager and more! ?mw 5. Each is run by a Head of Facility who is responsible for daily operations and ensuring high user satisfaction. Craig Praul: cap142@psu.edu: 814-865-4262: High Field Magnetic Resonance Imaging Facility (Huck) poster abstractThe Chemical Genomics Core Facility (CGCF) is a shared facility of the IU Simon Cancer Center and IU School of Medicine. The Chemical Genomics Facility (CGF) is a newly established facility at the Purdue Insitute for Drug Discovery. The Bioimaging and Chemical Analysis Facilities Core is a central resource in analytical chemistry, separation science, metabolomics, and proteomics for Center members, and provides research participants with analytical expertise, training, and access to state-of-the-art instrumentation. 2018 publications Heinitz, S., et al. The ASU Genomics Facility offers sequencing services and expertise for both traditional and next-generation applications. Core Facilities are staffed by technology experts who focus entirely on service provision, delivering technologies to be used in research projects designed and run by others. The core generates and characterizes iPSC lines from adult tissue samples, serves as a repository to conduct basic and translational research, and provides expertise on work involving human iPSCs. ;}hQKw,)]>nL]*32Th(k4ubz/H2h+IUor~UhbFFrUeF)%7I=rUr7A=c.VM~Ja~SgMF|iDWJ/dRV[+'4kgAPhLPw6rlOv[,eVsV:YUZVHvl"$/?5nV//d^u=K2~A0aEA6 The Clemson Light Imaging Facility (CLIF) is a multi-user core facility located on the main campus of Clemson University. Within the Genomics Core, DNA sequencing supports research across the campus and extends to projects in collaboration with other institutions, including the sequencing of genomes, RNASeq, ChIPSeq, methylSeq, metagenomics and other More about BioMS. Core facilities are physically housed and administered by Duke research institutes and centers, including the Duke Cancer Institute and the Duke Human Vaccine Institute. 3. The BPF NGS Genomics Core Facility provides state of the art resources and services including NextGen Sequencing on the Illumina platform, NGS Sample Preparation (for a variety of DNA and RNA applications), Single Cell Analysis on the 10X Genomics Chromium platform, DNA and RNA Quality Assessment, Sanger DNA Sequencing, DNA/RNA isolation and purification, Oligonucleotide Ordering, Genetics, Genomics, and Proteomics. Genomics and Bioinformatics. Discovery of small non-coding RNAs: ncRNA-Seq. Contact Jingwei Meng, PhD, to request high throughput screening service. More about this facility > Facility Category . Our dedicated staff has years of experience in academic drug discovery and within the pharmaceutical industry, allowing us to provide expert V_vqvtK#~G t3yv*. The Chemical Genomics Facility (CGF) is a facility at the Purdue Institute for Drug Discovery. 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